Curriculum vitae


Employment History  

I completed my medical degree in New Zealand and began my ophthalmology training in the UK as a Senior House Officer at the Sussex Eye Hospital, Brighton. I then took a Senior House Officer job at St Thomas' Hospital in London and went on to complete a retinal PhD at The Rayne Institute, St Thomas' Hospital. Following that I undertook a further four years of Registrar training based at Moorfields Eye Hospital, where I stayed on as a Vitreoretinal Fellow.  I now work as a Consultant Ophthalmic Surgeon at King's College Hospital, a large teaching hospital in South London.  I undertake cataract surgery and have a sub-specialty interest in macular and retinal surgery. I am a HEFCE Senior Lecturer at King's College London, part of the King's Health Partners, the UK's largest Academic Health Science Centre. My research interests and peer reviewed publications are given below.  Current interests include studies of ocular macromolecular diffusion and drug modification in relation to the pharmacotherapy of age-related macular degeneration (AMD), ocular safety testing using cell culture techniques, and studies investigating the vitreomacular interface and how this influences wet AMD. In addition, I am Editor of the Moorfields Manual of Ophthalmology.  I am currently UK Chief Investigator for the CABERNET study of epimacular brachytherapy, a new surgical treatment for wet age-related macular degeneration developed by NeoVista, and the MERITAGE study investigating the use of this device in patients who require frequent anti-VEGF (Lucentis/Avastin) therapy.   I also lead the MERLOT study of epimacular brachytherapy, one of the country's largest randomised controlled trials in ophthalmology (see www.merlotstudy.com). I have been closely involved in key studies of stereotactic radiotherapy for wet AMD, and the use of ocriplasmin for pharmacological vitreolysis. More recently I have been involved in the clinical trial of subretinal implants, the so-called 'bionic eye'. I supervise clinicians undertaking MDs and PhDs, serve as a specialist advisor to NICE, and am engaged as a Key Opinion Leader by Industry. Research income is approximately £3.2M since 2007.

Affiliations

Royal College of Ophthalmologists
General Medical Council
British Medical Association

Medical Protection Society
American Academy of Ophthalmologists
Euretina
British and Eire Association of Vitreoretinal Surgeons
Association for Research in Vision and Ophthalmology
Retina Society

Publications

TEXTBOOKS

 Jackson TL. Editor-in-Chief, Moorfields Manual of Ophthalmology.  Elsevier, London [for details click here.

BOOK CHAPTERS

Jackson TL, Egan C, Bird AC. Chapter 10. Medical Retina, Moorfields Manual of Ophthalmology.  Ed. Jackson TL. Elsevier 2008, London.

Jackson TL, Da Cruz LD, Gregor Z. Chapter  11. Surgical Retina, Moorfields Manual of Ophthalmology.  Ed. Jackson TL. Elsevier 2008, London.

Bates A, Jackson TL, Adams GGW. Chapter 12. Paediatric Ophthalmology. Moorfields Manual of Ophthalmology.  Ed. Jackson TL. Elsevier 2008, London.

Jackson TL  Chapter 11. Vital staining and retinal detachment surgery.   Vital Dyes in Vitreoretinal Surgery: Chromovitrectomy.  Ed. Meyer CH. Developments in Ophthalmology, Karger 2008, Bonn.

Petrarca R, Jackson TL. Chapter 22. Radiation for the treatment of wet age-related macular degeneration. Age-related macular degeneration: A comprehensive textbook. Lippincott, Williams and Wilkins 2012,  in press, Riverwoods. 

Simpson ARH, Jackson TL. Chapter 2. The epidemiology of vitreo-macular interface diseases.  In Diseases of the Vitreo-Macular Interface. Ed. Girach A, de Smet MD. Springer-Verlag 2012, in press. Berlin.

 PEER REVIEWED ARTICLES

Dugel PU, Bebchuk JD, Nau J, Reichel MD, Singer M, Barak A, Binder S, Jackson TL (for the CABERNET Study  Group). Epimacular brachytherapy for neovascular age-related macular degeneration: A randomized controlled trial (CABERNET). Ophthalmology in press.

Simpson ARH, Petrarca R, Jackson TL. Vitreomacular adhesion and neovascular age-related macular degeneration. Survey of Ophthalmology in press

Dugel P, Petrarca R, Bennett M, Barak A, Weinberger D, Nau J, Jackson TL. Macular epiretinal brachytherapy in treated age-related macular degeneration: MERITAGE study 12 month safety and efficacy results.  Ophthalmology in press

Jackson TL, Kirkpatrick L, Tang G, Prasad S. Cost analysis comparing adjuvant epimacular brachytherapy with anti-VEGF monotherapy for the management of neovascular age-related macular degeneration. Eye 2012;26:557-563.

Gupta B, Wong R, Laidlaw DAH, Jackson TL, McHugh D, Sivaprasad S, Williamson TH. Visual and anatomical outcomes following vitrectomy for complications of diabetic retinopathy (DRIVE UK Study). Eye 2012;26:510-516.

Petrarca R, Nau J, Dugel PU, Jackson TL. Epimacular brachytherapy for the treatment of retinal angiomatous proliferation. Retinal Cases and Brief Reports in press

Jackson TL, Hussain A, Salisbury J, Sherwood R, Sullivan PM, Marshall J. Transscleral albumin diffusion and suprachoroidal albumin concentration in uveal effusion syndrome. Retina 2012;32:177-182

Jackson TL, Kirkpatrick L. A cost comparison of ranibizumab and bevacizumab. British Medical Journal 2011;343:d5058

Stanescu-Segall D, Sebag M, Jackson T, Elagouz M. Modified 20-gauge transconjunctival pars plana vitrectomy.  Retina 2011;31:982-987.

Petrarca R, Jackson TL. Radiation therapy for neovascular age-related macular degeneration. Clinical Ophthalmology 2011;5:57-63

Elagouz M, Stanescu-Segall D, Jackson TL. Uveal effusion syndrome. Survey of Ophthalmology 2010;55:134-145 [Major Review].

Stanescu-Segall D, Jackson TL. Vital staining with indocyanine green: a review of the clinical and experimental studies relating to safety .  Eye 2009;23:504-18 [Perspective]

Jackson TL, Hussain A, Morley AMS, Sullivan PM, Hodgetts A, El-Osta A, Hillenkamp J, Charles SJ, Sheard R, Williamson TH, Kumar A, Laidlaw DAH, Woon HW, Costen MJ, Luff AJ, Marshall J. Scleral hydraulic conductivity and macromolecular diffusion in patients with uveal effusion syndrome. Investigative Ophthalmology and Visual Science 2008;49:5033-40.

Anderson OA, Jackson TL, Singh JK, Hussain AA, Marshall J. Human transscleral albumin permeability and the effect of topographical location and donor age. Investigative Ophthalmology and Visual Science 2008;49:4041-5.

Hillenkamp J, Kraus J, Framme C, Jackson TL, Roider J, Gabel VP, Sachs HG.  Retreatment of full-thickness macular hole: predictive value of optical coherence tomography. British Journal of Ophthalmology 2007;91:1445-1449.

Jackson TL, Kwan A, Laidlaw DAH, Aylward GW. Identification of retinal breaks using subretinal trypan blue injection. Ophthalmology 2007;114:587-590

Wang M, Zhang JJ, Jackson TL, Sun X, Wu W, Marshall J.  Safety and efficacy of intracapsular tranilast microspheres in experimental posterior capsule opacification. Journal of Cataract and Refractive Surgery 2007;33:2122-2128.

Saikia P, Maisch T, Kobuch K, Jackson TL, Bäumler W, Szeimies RM , Gabel VP, Hillenkamp J. Safety testing of indocyanine green in an ex vivo porcine retina model. Investigative Ophthalmology and Visual Science 2006;47:4998-5003.

Jackson TL, Hussain A, Noury AMS, Hodgets A, Hillenkamp J, Sullivan PM, Marshall J.  Human scleral hydraulic conductivity: age-related changes, topographical variation, and potential scleral outflow facility. Investigative Ophthalmology and Visual Science 2006;47:4942-4946.

Jackson TL.  Indocyanine green accused: the case for and against ICG assisted macular surgery. British Journal of Ophthalmology 2005;89:395-396. [Editorial]

Jackson TL, Griffin L, Vote B, Hillenkamp J, Marshall J. An experimental method for testing novel retinal vital stains. Experimental Eye Research 2005; 81:446-454.

Jackson TL, Vote B, Knight BC, El Amir A, Stanford MR, Marshall J. Safety testing of infracyanine green using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science 2004;45:3697-3703.

Jackson TL, Hillenkamp J, Knight B, Zhang, JJ, Thomas D, Stanford MR, Marshall J. Safety testing of indocyanine green and trypan blue using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science 2004;45:2778-2785

Jackson TL Safety testing of indocyanine green and trypan blue using retinal pigment epithelium and glial cell cultures. Investigative Ophthalmology and Visual Science Online. December 30, 2004 [Author comment].

Jackson TL. Safety of indocyanine green as a vital stain. Anesthesiology 2004;100;1330 [Letter].

Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. The influence of pathlength and matrix components on ageing characteristics of transport between the choroid and the outer retina. Investigative Ophthalmology and Visual Science 2004;45:1493-1498.

Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Compartmental analysis of taurine transport to the outer retina in the bovine eyes Investigative Ophthalmology and Visual Science 2004;45;4099-4105.

Hillenkamp J, Hussain AA, Jackson TL, Cunningham JR, Marshall J.  Taurine uptake by human retinal pigment epithelium: implications for the transport of small solutes between the choroid and the outer retina. Investigative Ophthalmology and Visual Science 2004;45;4529-4534.

Jackson TL, Ong GL, Ripley LG.  Orientational contrast sensitivity and chromatic contrast thresholds in multiple sclerosis.  American Journal of Ophthalmology. 2004; 137:283-286.

Jackson TL, Marshall J.  Fluorophore assisted retinal break detection using antibodies to glial fibrillary acidic protein. Investigative Ophthalmology and Visual Science 2004;45:993-1001.

Jackson TL, Hillenkamp J, Williamson TH, Clarke KW, Almubarak AI, Marshall J. An experimental model of rhegmatogenous retinal detachment: surgical results and glial cell response. Investigative Ophthalmology and Visual Science 2003; 44:4026-4034.

Jackson TL, Antcliff RJ, Hillenkamp J, Marshall J.  Human retinal molecular weight exclusion limit and estimate of species variation. Investigative Ophthalmology and Visual Science 2003; 44:2141-2146.

Jackson TL, Eykyn SJ, Graham EM, Stanford MR.  Endogenous bacterial endophthalmitis: A 17 year prospective series and review of 267 reported cases. Survey of Ophthalmology 2003; 48: 403-423 [Major Review].

Jackson TL, Ong GL, MacIndoe MA, Ripley LG.  Monocular chromatic discrimination threshold and achromatic contrast sensitivity in children born prematurely. American Journal of Ophthalmology 2003;136:710-719.

Jackson TL, Thiagarajan M, Murthy R, Snead MP, Wong D, Williamson TH.  Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection.  American Journal of Ophthalmology. 2002;134:634-635 [Author comment]

Jackson TL, Larson J, Tanner V, Williamson TH.  Combined phacoemulsification cataract extraction and pars plana vitrectomy without intraocular lens implant.  Ophthalmologica 2001;215:271-275.

Jackson TL, Thiagarajan M, Murthy R, Snead MP, Wong D, Williamson TH.  Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection.  American Journal of Ophthalmology. 2001;132:414-416

Tanner V, Chauhan DS, Jackson TL, Williamson TH. Optical coherence tomography of the vitreoretinal interface in macular hole formation.  British Journal of Ophthalmology 2001;85:1092-1097

Newsom RSB, Ong GL, Jackson TL, Ripley LG, Fisher M, Casswell TG.  Screening for CMV retinitis using chromatic discrimination thresholds and achromatic contrast sensitivity.  British Journal of Ophthalmology 2000;84:877-880.

Jackson TL, Meacock W, Graham EM. Severe intraocular inflammation after a change of HAART.  British Journal of Ophthalmology 2000;84:933-934 [Letter]

 Jackson T, Tanner V, Williamson TH.  Modified sutureless sclerotomies in pars plana vitrectomy. American Journal of Ophthalmology 2000;129:116-117 [Letter].

Jackson TL, Beun L. A prospective study of cost, patient satisfaction and outcome of treatment of chalazion by medical and nursing staff.  British Journal of Ophthalmology 2000;84:782-785.

Jackson TL, Farmer CKT, Kingswood C, Vickers S.  Hypotensive ischemic optic neuropathy and peritoneal dialysis.  American Journal of Ophthalmology 1999;128:109-111.

 Jackson TL, Williamson TH.  Amikacin retinal toxicity.  British Journal of Ophthalmology 1999;83(10):1199-1200 [Letter].

COMMISIONED ARTICLES

Petrarca R, Jackson T.  Radiation therapies for wet AMD. Optician 2012; in press.

Jackson TL. Radiation therapy for neovascular age-related macular degeneration. Ocular Times 2011; in press

Jackson TL. Deepen your understanding of uveal effusion syndrome. Retinal Physician 2010; Oct:49-53. 

Jackson TL. Epimacular brachytherapy: reducing neovascular AMD treatment burden. Retina Today 2010; Mar:77-79

Petrarca R, Jackson T.  Epimacular brachytherapy for the treatment of wet AMD. Optician 2009;6203(237):28-30.

Jackson TL. Treating wet AMD with radiation. Ophthalmology Times 2009:5(4).

Ramkissoon YD, Jackson TL, Charteris DG. Managing common retinal disorders. Practitioner 2006; 250: 1-4.


 PUBLISHED ABTRACTS

 Anderson O, Jackson TL, Hussain AA, Marshall. Human trans-scleral albumin diffusion and effect of cryopreservation. ARVO abstract  2006.

Jackson TL, Griffin L, Vote B, Hillenkamp, Marshall J. A systematic experimental method of screening novel retinal vital stains. ARVO abstract 2005.

 Anderson O, Jackson TL, Hussain AA, Marshall J. Human trans-scleral albumin diffusion and effect of cryopreservation. ARVO abstract 2005.

 Hillenkamp JM, Hussain AA, Jackson TL, Cunningham JR, Marshall J. Effect of Taurine and apical potassium concentration on eletrophysiology of bovine retinal pigment epithelium ARVO abstract 2005.

 Hillenkamp JM, Hussain AA, Jackson TL, Cunningham JR, Constable P, Marshall J. Transepithelial transport of taurine across isolated bovine retinal pigment epithelium. ARVO abstract 2004.

Hillenkamp JM, Hussain AA, Zhang JJ, Jackson TL, Cunningham JR, Marshall J. Age-related macular degeneration: metabolic insufficiency in the ageing retina?  ARVO abstract 2003.

Jackson TL, Hillenhamp J, El Osta A, Zhang JJ, Marshall J.  Safety testing of indocyanine green and trypan blue using a cell culture model. ARVO abstract 2003.

Jackson TL, Marshall J. Fluorophore assisted retinal break detection: In vivo studies using Cy3 tagged antibody to glial fibrillary acidic protein. ARVO abstract 2002.

Jackson TL, Antcliff RJ, Hodgetts A, Hussain AA, Hillenkamp J, Zhang JJ, Marshall.  Retinal exclusion limit: species variation. ARVO abstract 2001.

Noury AM, Jackson TL, Hodgetts A, Marshall J.  Hydraulic conductivity of sclera as a function of age. ARVO abstract 2001.

Hillenkamp J, Cunningham JR, Chauhan D, Jackson TL, Hussain AA, Zhang JJ, Marshall J: Diffusion of Taurine across bovine Bruch`s membrane and choroid. ARVO abstract 2001.

Jackson TL, Marshall J. Fluorophore assisted retinal break detection: Proof of principle using antibodies to glial fibrillary acidic protein. ARVO abstract 2000.

Noury AMS,
Jackson TL, Hodgetts A, Sullivan P, Marshall J. Scleral hydraulic conductivity in uveal effusion syndrome. ARVO abstract 2000.

 Jackson TL, Eykyn S, Stanford M, Graham E. Endogenous bacterial endophthalmitis, a diagnostic pitfall: 20 years experience at St Thomas’ Hospital and review of 230 reported cases. Fed Infect Dis 2000.

 Jackson TL, Ong GL, Pearson AR, Ripley LG. Orientational contrast sensitivity in patients with multiple sclerosis. ARVO abstract 1999.

 Ong GL, Newsom RSB, Jackson TL, Coldrick I, Ripley LG, Fisher M, Casswell AG. Achromatic and chromatic discrimination sensitivity in HIV patients with and without CMV retinitis. ARVO abstract 1998.

 Jackson TL, Ong GL, Ripley LG, Hughes P. An experimental evaluation of optic nerve function in multiple sclerosis patients undergoing controlled aerobic exercise with a constant core body temperature. ARVO abstract 1998.

 Poon WKM, Ong GL, Jackson TL, Ripley LG, Casswell AG. Chromatic discrimination can be used to predict the outcome of macular hole surgery.  ARVO abstract 1997.

 Jackson TL, Moate BJR, Knowles PJ, Ong GL, Poon WKM, Tregear SJ, Ripley LG, Casswell AG. Chromatic and achromatic contrast sensitivity in patients with HIV infection. ARVO abstract 1997.

 Pearson AR, Tregear SJ, Jackson TL, Harden AF, Ripley LG. Therapeutic levels of digoxin do not affect chromatic discrimination threshold.  ARVO abstract 1996.

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